1Adamu, Dalhatu, 1Hafsah Ibrahim Garba,1Muhamad Yusuf Muhamad3, Nuhu Lawan Adamu2,
1Department of Nursing Science, Bayero University Kano-Nigeria
2Department of Nursing Sciences, Modibbo Adama University, Yola
3Department of Community Medicine, Bayero University Kano.
*Corresponding author’s Email: adamudalhatu206@gmail.com, doi.org/10.55639/607.020100102
ABSTRACT
Chronic kidney disease (CKD) is a major cause of morbidity and mortality globally, including in Nigeria. Although gender-related disparities in CKD have been described, limited quantitative evidence exists from tertiary nephrology settings in Northern Nigeria evaluating sex differences in disease severity. This hospital-based cross sectional analytical study included 190 adults with confirmed CKD attending Aminu Kano Teaching Hospital. CKD staging was determined using the CKD-EPI 2021 equation and classified according to KDIGO 2023 guidelines. Advanced CKD was defined as Stage 4–5 (eGFR < 0.001) were independently associated with advanced CKD. Male sex was not independently associated with disease severity (AOR = 1.29; 95% CI: 0.63–2.63; p = 0.476). Significant sex differences were observed in reported healthcare access barriers (p = 0.033), with women more frequently reporting financial constraints. In this tertiary nephrology population, advanced CKD was common and primarily associated with hypertension and diabetes rather than sex alone. While gender differences in reported healthcare access were observed, sex was not independently associated with CKD severity. Strengthening early cardiometabolic disease control may reduce advanced CKD presentation in similar settings.
KEYWORDS
CKD,
Advanced CKD,
Gender-differences,
Hypertension.
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