Glycaemic response to chromic catgut and polyglycolic acid sutures post-rumenotomy following Diazepam-Lidocaine-Bupivacaine Anaesthesia in Sahel Goats

Abubakar Mshelia Saidu*, Paul Bitrus Bokko and Abdullahi Mohammed

Department of Veterinary Surgery and Radiology, University of Maiduguri, Maiduguri, Borno State, Nigeria

*Corresponding author: abubakarsm51@gmail.com, doi.org/10.55639/607.4959


ABSTRACT

Glycaemic indices could serve as a biomarker of surgical stress; however, this is unclear in the goat. The experiment evaluated periodic levels of blood glucose as stress biomarker following rumenotomy with assorted sutures and local anaesthetics in prevailing Sahel region conditions among Sahel Goats. Blood samples 5mls each were collected from jugular veins of 15 goats that were randomly allocated into groups A, B and C to establish base line data before commencement of treatments. Blood was also collected at five minutes post anaesthetic induction (PAI) with diazepamlidocaine and diazepam-bupivacaine for groups A and B respectively. Rumen Skin Clamp Fixation Technique of rumenotomy was employed followed by further blood sampling immediately post surgery at 0 hour and subsequently at 5, 8, 24, 48 and 72 hours postoperatively. Glucose assay was conducted immediately at the time of each blood sample collection. The periodic blood glucose profile for goats in group A were significantly high (P < 0.05) at PAI, (94.60±19.55 mg/dl) and zero hour, (101.4±21.35 mg/dl) post-surgery when compared to respective baseline value (57.20±4.15 mg/dl) and similarly for group B at PAI (107.4±28.40 mg/dl) and zero hour (119.8±34.48 mg/dl) hours compared to its baseline value (64.80±4.09). These values declined continuously through 5, 8-, 24-, 48- and 72-hours post-surgery for both groups. The significant rise in blood glucose level in both approaches 5 minutes PAI and immediately after surgery that averagely lasted 40 minutes were only transitory and cannot be used as reliable biomarker of stress because the pattern does not appear to be in consonance with stress profile post-surgery.

Keywords:

Glucose,
Rumenotomy,
Sutures,
Local Anaesthesia,
Diazepam