In-vitro Studies on the Herbal Plant Microdesmis keayana Methanol Leaves Extract Phytocomponents by GC-MS Analysis: A Further Evidence for its Phytomedicinal Potentials in Enhancement of Reproductive Functions

*Adekunle Orimisan OJATULA and Ndubuisi NWANJA

PhytoMedicine and PhytoPharmacology Research Group, Botany Unit, Department of Biological Sciences, School of Science, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria

*Corresponding author:,


Microdesmis keayana (Microdesmis) belongs to the Pandaceae family, and it is called “Apata” in Yoruba South-Western Nigeria. The study is undertaken determining the availability or absence of erectile and pro-fertility compounds of the methanol extract of leaves of Microdesmis keayana by mass spectroscopy using gas chromatography (GC-MS). Methodologically, GC-MS analysis was used. The GC-MS analysis revealed six (6) peaks corresponding to six distinct phytoconstituents which include: 9, 12-Octadecadienoic acid (Linoleic acid) (peak area: 22.99%), 11- Phenylundecanoic acid (peak area: 17.66%), 2,4-Dihydroxy-2,5- dimethyl-3(2H)-furan-3-one (peak area: 21.14%), Squalene (peak area: 14.01%), n-Hexadecanoic acid (peak area: 13.11%), and Stigmasterol (peak area: 11.09%) respectively. Sequel to the findings of this study, methanol extract of Microdesmis keayana leaves may be an effective reproductive therapeutic agent, paving the way for the development of several treatment regimens based on compounds derived from this extract.


Microdesmis keayana,
linoleic acid,